Simone Arceneaux 
Matt Damon broke through by co-writing and starring in “Good Will Hunting,” winning an Oscar for the screenplay, and went on to anchor the Bourne franchise and films like “The Martian” and “Oppenheimer.”
Leonardo DiCaprio became a global star with “Titanic” and built one of Hollywood’s most respected careers through films like “The Departed,” “Inception” and “The Revenant,” which earned him an Oscar.
Australian actor Hugh Jackman became a global star as Wolverine in the X-Men films while building a parallel career as a Tony-winning musical theater performer.
Sandra Bullock became a star with Speed, ruled romantic comedy in the 1990s and 2000s, then won an Academy Award for The Blind Side and anchored the space thriller Gravity.
George Clooney spent years in small TV roles before ER made him a star. He went on to win two Academy Awards, direct films and co-found an organization that investigates war crimes.